PEGylated G-CSF (BBT-015), GM-CSF (BBT- 007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome.
Plett PA, Chua HL, Sampson CH, Katz BP, Fam CM, Anderson LA, Cox GN, Orschell CM
Health Physics Journal 106: 7-20, 2014.
Site-specific protein PEGylation: application to cysteine analogs of recombinant human granulocyte colony-stimulating factor.
Rosendahl MS, Doherty DH, Smith DJ, Bendele AM, Cox GN.
BioProcess International 3 (4): 52-62, 2005.
Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein.
Cox GN, Smith DJ, Carlson SJ, Bendele AM, Chlipala EM, Doherty DH.
Experimental Hematology 32: 441-449, 2004.
Hematopoietic properties of granulocyte colony-stimulating actor / immunoglobulin fusion proteins (G-CSF/IgG-Fc) in normal and neutropenic rodents.
Cox, GN, Chlipala EA, Smith DJ, Carlson SJ, Bell SJ, Doherty DH.
PLOS ONE Mar 17;9(3):e91990. doi: 10.1371/journal.pone.0091990, 2014.